Geographic tongue is a chronic, inflammatory, and immune-mediated oral lesion of unknown etiology. We believe that this article may be useful in guiding clinicians on the choice of treatment. Therefore, we performed a systematic review of benign migratory glossitis to identify the best evidence-based treatment available for this condition. Treating this disease is a formidable challenge for clinicians. In clinical practice, at the outpatient clinic of oral medicine, we attend to many patients diagnosed with benign migratory glossitis, with varying intensity of pain ranging from mild to severe. In summary, we could identify no specific treatment for symptomatic benign migratory glossitis. There is a very low level of evidence for the treatment of symptomatic benign migratory glossitis, with substantial methodological heterogeneity among the evaluated studies. Multiple treatment modalities were described for the treatment of symptomatic benign migratory glossitis. Of the 840 identified studies, 11 were included in our sample. The protocol for this systematic review was registered at the international prospective register of systematic reviews (PROSPERO) as CRD42017074096. We considered only articles published in English that evaluated the treatment of symptomatic benign migratory glossitis in children and adults. We searched the Cochrane Library, EMBASE, LILACS, PubMed, Scopus, and Web of Science for articles published up to September 2017, with no time restriction. The aim of this systematic review is to summarize the results of all published studies on symptomatic benign migratory glossitis and evaluate the best available treatment. Management of symptomatic geographic tongue. Results of the present study suggest that topical application of 0.1% tacrolimus is beneficial in the The overall treatment response was significantly better in Group A than Group B. Results: Patients in Group A (0.1% topical tacrolimus)ĭepicted lower scores of burning sensation after the treatment as compared to Group B (placebo). Social Sciences (SPSS) Statistics version 21. Data were assessed using IBM Statistical Package for Tested through Tel Aviv‑San Francisco Scale. At each visit, theīurning sensation was tested through the Visual Analog Scale and the treatment responses were Ointment (Protopic®) in an oral base on their lesions and an identical placebo. Patients were requested to apply 0.1% topical tacrolimus Involving a total of 14 patients who were randomly divided into two groups, namely Group A and

Materials and Methods: This was a prospective study The present study aims to evaluate the response of treatment with topical tacrolimus ointmentĠ.1% w/w (Protopic®) in geographic tongue. There is no definite treatment for geographic tongue as yet.

Background: Geographic tongue is characterized by erythematous patches with whitish marginsĪcross the surface of the tongue, with periods of exacerbation and remission that confer the

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